

DARK SPOTS & HYPERPIGMENTATION SKIN CARE SOLUTIONS & TREATMENT
SKIN CARE ROUTINE FOR DARK SPOTS & FACE DISCOLORATION
WHAT IS HYPERPIGMENTATION?
The term "dark spots" is a generic definition for multiple forms of hyperpigmentation including sun damage, age spots, melasma, discoloration, uneven skin tone, and more. Hyperpigmentation is caused by a variety of factors but is typically a result of cumulative sun exposure, environmental stressors, hormones, as well as medications and wounding - making it a challenge that nearly everyone faces as they age. In fact, the presence of uneven pigmentation and dark spots is so closely associated with aging, that studies have shown that the degree of hyperpigmentation is directly linked to a person's perceived age, even in the absence of wrinkles.
The good news is that you can reduce the visible signs of sun damage and prevent future damage today!
WHAT CAUSES HYPERPIGMENTATION & DARK SPOTS?
Pigment in the skin is produced by cells called melanocytes found in the basal, or bottom, layer of the epidermis.

These cells are dendritic; meaning they have dendrites that look like tiny fingers extending up through the upper layers of skin to release melanin, or pigment, into the cells around them.

While everyone has the same number of melanocytes, those with darker skin tones simply have more active melanocytes to provide pigment to the skin.

With discoloration, however, regions of melanocytes begin expressing excess levels of melanin for your individual skin type - leading to spots or non-uniform color.

Despite being one of, it not the most common signs of aging, hyperpigmentation is one of the most difficult conditions to address and can take months to show improvement.
HOW TO ADDRESS FACE DISCOLORATION & HYPERPIGMENTATION WITH SKIN CARE TIPS
The key to addressing face hyperpigmentation and age spots is to inhibit the production of excess melanin and to resurface skin to life with the color already released into surrounding skin cells.
KEY SKINCARE INGREDIENTS TO ADDRESS FACE PIGMENTATION
Tyrosinase Inhibitors
There are a range of ingredients called "tyrosinase inhibitors" that inhibit the production of the tyrosinase enzyme to prevent the formation of excess melanin in the skin. Examples of proven tyrosinase inhibitors include alpha arbutin, licorice root, turmeric, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Extra, and hexylresorcinol. Each of these tyrosinase inhibitors works a little differently so it is vital to utilize a variety of them to take a comprehensive approach to battling pigment.
Retinoids
Retinol is both a tyrosinase inhibitor and a resurfacing agent to lift pigment that has already been interspersed into surrounding skin cells. Retinol is a powerhouse ingredient that can also help build collagen to address lines and wrinkles and restore youthful, clear, and supple-looking skin.
Skin Resurfacing Acids
Skin Resurfacing Acids such as glycolic acid, azelaic acid, and salicylic acid have been shown to resurface skin, increase volume, inhibit tyrosinase, and provide anti-inflammatory benefits to reduce excess melanin production and lift existing pigment in the skin. When combined, this power trio of acids will address a wide range of skin concerns on anyone's list to provide overall radiant and flawless skin!
Targeted Lightening Ingredients
Targeted Peptides like nonapeptide-1, which is a lightening peptide, prevent melanin synthesis and unwanted pigmentation. Targeted ingredients like non-staining turmeric contain a component called curcumin which is a powerful anti-inflammatory and an antioxidant that plays a big role in reducing excess production of melanin.
Antioxidants
Additional antioxidants such as Vitamin C, green tea extract, and bisabolol can also play a role in reducing inflammation and preventing the production of excess pigment.
Sunscreen
Preventing future dark spots requires a combination of sun protection and the use of a proper home care regimen with skin care products for dark spots.
SKIN CARE PRODUCTS & SOLUTIONS DESIGNED TO PREVENT HYPERPIGMENTATION

Marini Luminate®
A long-term, non-hydroquinone solution that demonstrated exceptional results in the first month of use with continued improvement over time.
- Nonapeptide-1
- Tetrahydro Diferuloylmethane (colorless, non-staining turmeric)
- Alpha-Arbutin
- Hexylresorcinol
- Dipotassium Glycyrrhizate
- Licorice Root Extract
- All-Trans-Retinol
- Epigallocatechin Gallate (concentrated green tea extract)
- Bisabolol

Marini Luminate® Face Mask
Advanced mask that visibly brightens and gently exfoliates for smooth, healthy, and glowing skin.
- ChromabrightTM
- Alpha-Arbutin
- Dipotassium Glycyrrhizate
- Lactic Acid
- Mandelic Acid
- Green Tea Extract
- White Tea Extract
- Red Tea Extract
- Kaolin
To achieve the best results, combine Age Intervention Retinol Plus with the Skin Care Management System!

Skin Care Management System™
The most awarded product by NewBeauty Magazine and #1 Best System!
A comprehensive collection of advanced products delivers rapid improvement in the appearance of fine lines and wrinkles, uneven texture, and sun damage.
- Peptides
- Growth factors
- AHA & BHA resurfacing acids
- Vitamin C
- Hydrators
- Broad-spectrum sunscreen







Hyperpigmentation Study
Split-Face Comparison of an Advanced Non-Hydroquinone Lightening Solution to 4% Hydroquinone
Joel Schlessinger, MD
Study Summary:
- Outperformed gold-standard 4% hydroquinone (Obagi)
- Equal or superior reduction in hyperpigmentation vs. hydroquinone at all time intervals
- Statistically significant improvement in wrinkles
- 2:1 subject preference over Obagi hydroquinone

Marini Luminate Face Lotion Clinical Study
Study Summary:
- Statistically significant improvement in the appearance of hyperpigmentation, fine lines, and wrinkles
- Rapid improvement with results after only 4 weeks
- Continued improvement over the course of the study

